Site specific cross linking of collagen peptides by lysyl advanced glycation endproducts Chemical Communications (RSC Publishing) Modulation of Fibroblast Phenotype and Collagen Synthesis by GHK Cu in Prime Lab Peptides How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin GHK Cu 50mg Copper Peptide Peptides Alpha Proteolytic processing of lysyl oxidaselike 2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV Journal of Biological Chemistry JCI 11 Hydroxysteroid dehydrogenase blockade prevents age induced skin structure and function defects