Simplify your Glutathione Measurements Arbor Assays Heinz bodies are small clumps of damaged hemoglobin found inside red blood cells. They form due to oxidative stress and are often seen in conditions like G6PD deficiency. Their presence can indicate In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl Hemoglobin Redox Pairs In Vitro and In Vivo The Redox Process in Red Blood Cells: Balancing Oxidants and Antioxidants What is the mechanism of glutathione reductase when reducing oxidized glutathione? Quora